Working with RNA
mRNA is a groundbreaking technology with transformative applications in medicine, diagnostics, agriculture, and marine biology.
RNA, or ribonucleic acid, is a versatile molecule that plays a central role in protein synthesis and cellular functions. Types of RNA include messenger RNA (mRNA), transfer RNA (tRNA), interfering RNA (RNAi or siRNA), microRNA (miRNA) and ribosomal RNA (rRNA), each with distinct functions. In medicine, mRNA transformed vaccines and therapies by leveraging its ability to encode proteins. mRNA vaccines, like those for COVID-19, deliver synthetic mRNA to cells, prompting them to produce antigens that trigger immune responses. RNA therapies include gene replacement, RNA interference (RNAi) for silencing disease-causing genes, and self-amplifying RNA for enhanced efficacy. These technologies enable rapid development, precision targeting, and non-integrative treatments, offering innovative solutions for infectious diseases, genetic disorders, autoimmune disorders and cancer.
mRNA in healthcare
mRNA in agriculture
mRNA in marine biology
Work with us
Our scientists have experience in the discovery and development of mRNA molecules. We can provide end-to-end research services for pre-clinical development of mRNA.
What we do
mRNA Synthesis and Modification
We offer high-throughput manufacturing and screening of DNA and RNA sequences, including modifications such as 5’ capping and polyA tail addition.
AI-Driven mRNA Sequence Design
We design synthetic mRNA using an AI approach to optimise sequences for stability, expression levels, and immunogenicity.
DNA Template and Plasmid Design and Production
With extensive combinatorial DNA cloning expertise, we generate DNA plasmids and sequences for new mRNA products.
Lipid Nanoparticle Formulation and Quality Control
We ensure high-quality mRNA production and lipid nanoparticle formulation with rigorous quality assurance processes.
Our pricing model
The RIF facility is a “front door” for researchers that are keen to engage with RNA as a novel platform for various therapeutic and other avenues. We offer collaborative projects and service projects for UWA researchers, associates and industry. Contact us for more information.
Location and contact
Contact
Connect with us
Bayliss Building (M310)
Lab 4.21, Level 4, Bayliss Building (access via Fairway Entrance 4)
The University of Western Australia
Crawley (Perth) Campus
35 Stirling Highway
Perth WA 6009
Australia